Description

Ethyl L-Methionate Hydrochloride is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. Its primary value lies in providing a versatile intermediate for the preparation of peptides, peptidomimetics, and other bioactive molecules with controlled stereochemistry. This compound is particularly critical for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular construction.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Peptide Chemistry: Serves as a protected methionine derivative in solid-phase and solution-phase peptide synthesis.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog in metabolic pathway investigations.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	Ethyl L-Methionate Hydrochloride
CAS No.	2899-36-7
Molecular Formula	C7H15NO2S • HCl
Molecular Weight	213.72 g/mol
Synonyms	L-Methionine Ethyl Ester Hydrochloride; (S)-2-Amino-4-(methylthio)butanoic Acid Ethyl Ester Hydrochloride; Ethyl L-2-Amino-4-(methylthio)butyrate Hydrochloride; H-Met-OEt • HCl; Methionine Ethyl Ester HCl; Ethyl (S)-2-Amino-4-(methylsulfanyl)butanoate Hydrochloride; L-Methionine Ethyl Ester Monohydrochloride
EINECS	220-795-1

Quality Control

Our Ethyl L-Methionate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess), chemical assay, and impurity profiling, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chloride Content (Titration)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.