Description

Bromonordiazepam is a benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in neuropharmacology and medicinal chemistry. The product is supplied to meet the stringent demands of high-purity chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel benzodiazepine-based therapeutic agents.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Metabolite Studies: Employed in pharmacological and toxicological research to study drug metabolism pathways.
• Medicinal Chemistry Research: A vital scaffold for structure-activity relationship (SAR) studies aimed at discovering new central nervous system (CNS) active compounds.
• Analytical Testing: Serves as an impurity standard or system suitability standard in chromatographic analyses (e.g., HPLC, GC).

Basic Information

Product Name	Bromonordiazepam
CAS No.	2894-61-3
Molecular Formula	C₁₅H₁₀BrN₃O
Molecular Weight	328.16 g/mol
Synonyms	7-Bromo-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Bromonordiazepam; 7-Bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; Desmethyldiazepam 7-bromo derivative; Ro 05-2921; Bromodesmethyldiazepam
EINECS	Contact for details

Quality Control

Our Bromonordiazepam is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Standard quality parameters include assay by HPLC, control of related substances, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.