Description

1,3-Dihydro-7-(Methylthio)-5-Phenyl-2H-1,4-Benzodiazepine-2-One is a specialized benzodiazepine derivative, a key chemical class in pharmaceutical research and development. This compound serves as a crucial advanced intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and for structure-activity relationship (SAR) studies. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic compounds with potential anxiolytic, sedative, or anticonvulsant properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the mechanism of action of benzodiazepines at GABA-A receptors.
• Process Development: Used in scaling up and optimizing synthetic routes for complex pharmaceutical molecules.

Basic Information

Product Name	1,3-Dihydro-7-(Methylthio)-5-Phenyl-2H-1,4-Benzodiazepine-2-One
CAS No.	2891-12-5
Molecular Formula	C₁₆H₁₄N₂OS
Molecular Weight	282.36 g/mol
Synonyms	7-(Methylthio)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Methylmercapto-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-Phenyl-7-(methylthio)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Methylthio-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one; NSC 113928; 1,4-Benzodiazepine-2-one, 1,3-dihydro-7-(methylthio)-5-phenyl-
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-7-(Methylthio)-5-Phenyl-2H-1,4-Benzodiazepine-2-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.