Description

7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2H-Benzo-1,4-Diazepin-2-One 4-Oxide is a key benzodiazepine derivative and a crucial synthetic intermediate in pharmaceutical manufacturing. This compound matters for its role in the development of active pharmaceutical ingredients (APIs) and advanced research into central nervous system (CNS) therapeutics. It is primarily needed by pharmaceutical R&D laboratories, fine chemical synthesis facilities, and manufacturers of specialty chemical building blocks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting the central nervous system.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Synthesis: Employed as a specialized building block for constructing complex heterocyclic compounds in fine chemical production.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research for related pharmaceutical compounds.

Basic Information

Product Name	7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2H-Benzo-1,4-Diazepin-2-One 4-Oxide
CAS No.	2888-64-4
Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74 g/mol
Synonyms	7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide; 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one 4-oxide; Desmethyldiazepam N-Oxide; Nordazepam N-Oxide; 1-Methyl-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide; 2888-64-4; 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide
EINECS	220-771-5

Quality Control

Our 7-Chloro-1,3-Dihydro-1-Methyl-5-Phenyl-2H-Benzo-1,4-Diazepin-2-One 4-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.