Description

S-[(S)-2-Amino-2-Carboxyethyl]-L-Homocysteine is a specialized, high-purity amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and a key intermediate in the synthesis of complex peptides and enzyme inhibitors. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic pathway studies, drug discovery, and the production of high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting metabolic and cardiovascular diseases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to sulfur amino acid metabolism and transsulfuration pathways.
• Peptide Synthesis: Serves as a specialized, protected amino acid derivative for the solid-phase or solution-phase synthesis of bioactive peptides.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and NMR for quality control and method validation in pharmaceutical analysis.
• Nutritional Science Research: Investigated for its role in homocysteine metabolism and related nutritional studies.
• Enzyme Mechanism Studies: Utilized to probe the active sites and mechanisms of cystathionine β-synthase and other PLP-dependent enzymes.

Basic Information

Product Name	S-[(S)-2-Amino-2-Carboxyethyl]-L-Homocysteine
CAS No.	2867-15-4
Molecular Formula	C7H14N2O4S
Molecular Weight	222.26 g/mol
Synonyms	L-Cystathionine; (S)-2-Amino-4-((S)-2-amino-2-carboxyethylthio)butyric acid; S-(3-Amino-3-carboxypropyl)-L-homocysteine; L-α-Amino-γ-(S-2-amino-2-carboxyethylthio)butyric acid; L-Cystathionine (isomer); Homolanthionine ketimine precursor; 2867-15-4
EINECS	220-689-8

Quality Control

Our S-[(S)-2-Amino-2-Carboxyethyl]-L-Homocysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing lot-specific data for identity, purity, and impurities is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L,L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.