Description

5-(Aminomethyl)-2-(Trifluoromethyl)Pyrimidin-4-Amine is a high-value pyrimidine derivative featuring both an aminomethyl and a trifluoromethyl substituent, making it a versatile and reactive building block for advanced synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-containing scaffold can impart enhanced metabolic stability and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers with specific functional properties.
• Bioconjugation & Probe Synthesis: The reactive amine group facilitates its use in creating fluorescent probes, biomarkers, and other bioconjugates for diagnostic applications.

Basic Information

Product Name	5-(Aminomethyl)-2-(Trifluoromethyl)Pyrimidin-4-Amine
CAS No.	2822-73-3
Molecular Formula	C6H7F3N4
Molecular Weight	192.14 g/mol
Synonyms	4-Amino-5-(aminomethyl)-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)-5-(aminomethyl)pyrimidin-4-amine; 5-(Aminomethyl)-2-(trifluoromethyl)-4-pyrimidinamine; 4-Pyrimidinamine, 5-(aminomethyl)-2-(trifluoromethyl)-; 2822-73-3; 5-Aminomethyl-2-trifluoromethylpyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our production of 5-(Aminomethyl)-2-(Trifluoromethyl)Pyrimidin-4-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.