Description

D-Threonine, n-Methyl- CAS NO 2812-27-3 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry and methylation pattern. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries where precise molecular configuration is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, antibiotic, and enzyme inhibitor drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce specific structural and functional modifications into peptide chains.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies, enzyme-substrate interaction research, and as a precursor for labeled compounds.
• Agrochemical Development: Intermediate in the creation of novel, chiral herbicides and pesticides with improved selectivity and environmental profiles.
• Fine Chemical Production: Building block for synthesizing complex organic molecules, ligands for catalysis, and specialty chemicals.

Basic Information

Product Name	D-Threonine, n-Methyl-
CAS No.	2812-27-3
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2R,3S)-2-Amino-3-methoxybutanoic acid; D-α-Amino-β-methoxybutyric acid; (2R,3S)-3-Methoxy-D-threonine; Methyl-D-threonine; D-3-Methoxythreonine; D-β-Methoxythreonine; N-Methyl-D-threonine; D-Thr(Me)
EINECS	220-571-4

Quality Control

Our D-Threonine, n-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.