Description

L-Serine Methyl Ester is a protected derivative of the essential amino acid L-serine, widely used as a key chiral building block in organic synthesis. Its primary value lies in providing a versatile intermediate for constructing complex peptide and pharmaceutical molecules while preserving stereochemical integrity. This compound is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), peptide hormones, and specialized biochemical reagents.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of complex APIs, antiviral drugs, and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate serine residues while protecting the side-chain hydroxyl group.
• Biochemical Research: Serves as a precursor for labeled compounds, metabolic studies, and the preparation of specialized amino acid analogs.
• Agrochemical Development: Employed in the research and synthesis of novel, biologically active compounds for crop protection.
• Cosmetic Peptides: A building block for synthesizing bioactive peptides used in advanced skincare and cosmetic formulations.
• Ligand and Catalyst Preparation: Utilized in the development of chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	L-Serine Methyl Ester
CAS No.	2788-84-3
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	L-Serine methyl ester; Methyl L-serinate; (S)-2-Amino-3-hydroxypropanoic acid methyl ester; Ser-OMe; H-Ser-OMe; L-Serine, methyl ester; Methyl (S)-2-amino-3-hydroxypropanoate; NSC 404087
EINECS	220-511-6

Quality Control

Our L-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.