Description

2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenol is a highly fluorinated phenolic compound, distinguished by its unique electronic and steric properties imparted by the fluorine substituents. This compound is a critical advanced intermediate for the synthesis of complex molecules, particularly in high-value, performance-driven sectors. It is primarily sought by pharmaceutical, agrochemical, and specialty materials manufacturers for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated drug candidates, leveraging fluorine's ability to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of next-generation herbicides, pesticides, and fungicides, where the fluorinated phenol moiety contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to desired dielectric anisotropy and thermal stability.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a protecting group or directing agent in complex organic transformations due to its distinct reactivity.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenol
CAS No.	2787-79-3
Molecular Formula	C7H2F7O
Molecular Weight	232.08 g/mol
Synonyms	Pentafluorophenol, 4-(Trifluoromethyl)-; 4-(Trifluoromethyl)-2,3,5,6-tetrafluorophenol; 2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenol; 4-(Trifluoromethyl)pentafluorophenol; α,α,α,2,3,5,6-Heptafluoro-p-cresol; Heptafluoro-p-cresol; 4-Hydroxy-2,3,5,6-tetrafluorobenzotrifluoride
EINECS	220-509-6

Quality Control

Our production of 2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenol adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.