Description

4-Guanidinophenylalanine is a specialized amino acid derivative featuring a guanidino functional group attached to the phenylalanine core. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel bioactive compounds and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or protein-protein interactions.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a guanidino-modified phenylalanine residue, which can enhance binding affinity and stability.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and proteomics research.
• Enzyme Substrate/Analogue: Potential use in developing substrates or inhibitors for enzymes like trypsin-like proteases that recognize arginine or lysine residues.
• Chemical Biology Probes: Useful for creating labeled probes to study biological processes involving guanidino-group recognition.
• Material Science: Exploration into functionalized polymers or biomaterials where the guanidino group can impart specific chemical properties.

Basic Information

Product Name	4-Guanidinophenylalanine
CAS No.	2776-36-5
Molecular Formula	C10H14N4O2
Molecular Weight	222.25 g/mol
Synonyms	4-Guanidino-DL-phenylalanine; 4-(Diaminomethylideneamino)phenylalanine; p-Guanidinophenylalanine; 2-Amino-3-(4-guanidinophenyl)propanoic acid; Fmoc-4-guanidino-L-phenylalanine (precursor); 4-GPA; Guanidino phenylalanine; (4-Guanidino)phenylalanine
EINECS	Contact for details

Quality Control

Our 4-Guanidinophenylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.