Description

(5Alpha,17Beta)-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol 17-Acetate is a high-purity, photoaffinity-labeled steroid derivative, a critical tool for advanced biochemical and pharmacological research. This compound is specifically engineered for covalent binding studies, enabling the precise mapping of steroid hormone receptor sites and interaction mechanisms. It is an essential reagent for pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on endocrinology, drug discovery, and molecular biology.

Application

• Photoaffinity Labeling: A key reagent for covalent cross-linking studies to identify and characterize steroid-binding proteins and receptor targets.
• Drug Discovery Research: Used in high-throughput screening and mechanism-of-action studies for novel therapeutics targeting hormonal pathways.
• Biochemical Probes: Serves as a molecular probe in affinity chromatography and pull-down assays to isolate specific biomolecules.
• Metabolic Pathway Analysis: Employed in tracer studies to investigate steroid metabolism and biosynthesis in biological systems.
• Diagnostic Development: Utilized in the development of advanced immunoassays and diagnostic kits for hormonal disorders.
• Academic Research: Fundamental tool for university and institutional labs studying steroid hormone action, receptor biology, and signal transduction.

Basic Information

Product Name	(5Alpha,17Beta)-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol 17-Acetate
CAS No.	2760-21-6
Molecular Formula	C23H34N2O2
Molecular Weight	370.53 g/mol
Synonyms	17β-Hydroxy-5α-androstan-3α-yl diazirine-3'-carboxylate; 5α-Androstan-17β-ol-3α-yl 3-(3H-diazirin-3-yl)propionate; 3-(3H-Diazirin-3-yl)-5α-androstan-17β-yl propanoate; Androstane Diazirinyl Acetate; Photoaffinity Androstane Label; [3H]Diazirinyl Androstanol Acetate; 2760-21-6; Diazirine-modified steroid
EINECS	Contact for details

Quality Control

We supply (5Alpha,17Beta)-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol 17-Acetate with a focus on high radiochemical and chemical purity to meet the stringent demands of research applications. Our products undergo rigorous quality testing, including HPLC and NMR analysis, to ensure batch-to-batch consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This compound is strictly light-sensitive and must be protected from all light exposure during storage and handling to maintain stability and activity. Allow the container to reach room temperature in a dark environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Activity	Customizable (Contact for details)
Solubility	Soluble in common organic solvents (e.g., DMSO, ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.