Description

L-Thioproline is a sulfur-containing amino acid derivative, specifically the thio-analogue of proline. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel compounds and studying biochemical pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential therapeutic agents, including enzyme inhibitors and peptide mimetics.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway investigations due to its structural similarity to proline.
• Peptide Chemistry: Incorporated into synthetic peptides to modify their structure, stability, and biological activity.
• Fine Chemical Synthesis: Serves as a specialized reagent in asymmetric synthesis and the preparation of complex organic molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-Thioproline
CAS No.	2756-91-4
Molecular Formula	C5H9NO2S
Molecular Weight	147.20 g/mol
Synonyms	(2S)-1,3-Thiazolidine-4-carboxylic Acid; L-4-Thiazolidinecarboxylic Acid; (S)-(-)-Thiazolidine-4-carboxylic Acid; T4C; NSC 130103; L-Thiazolidine-4-carboxylic Acid; L-Proline, thio-; (S)-Thiazolidine-4-carboxylic Acid
EINECS	220-406-1

Quality Control

Our L-Thioproline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	-95° to -105° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.