Description

5-Ethyldihydro-5-Phenyl-2-Thioxopyrimidine-4,6(1H,5H)-Dione is a specialized heterocyclic organic compound belonging to the pyrimidinedione class, serving as a key synthetic intermediate and building block in advanced chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and high-value fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel therapeutic agents, particularly in the development of central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its heterocyclic core contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other high-value specialty chemicals requiring complex nitrogen-containing heterocycles.
• Academic & Industrial Research: A valuable reagent in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.
• Material Science: Investigated for potential use in the development of organic electronic materials and advanced polymers.

Basic Information

Product Name	5-Ethyldihydro-5-Phenyl-2-Thioxopyrimidine-4,6(1H,5H)-Dione
CAS No.	2753-74-4
Molecular Formula	C12H12N2O2S
Molecular Weight	248.30 g/mol
Synonyms	5-Ethyl-5-phenyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 5-Ethyl-5-phenyl-2-thiobarbituric acid; 5-Ethyl-5-phenyl-2-thioxo-1,3-diazinane-4,6-dione; 5-Phenyl-5-ethyl-2-thiobarbituric acid; NSC 403697; 2-Thio-5-ethyl-5-phenylbarbituric acid; 5-Ethyl-5-phenyl-2-thiobarbituric acid; 2-Thioxo-5-ethyl-5-phenylpyrimidine-4,6(1H,5H)-dione
EINECS	220-406-1

Quality Control

Our 5-Ethyldihydro-5-Phenyl-2-Thioxopyrimidine-4,6(1H,5H)-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents, supporting compliance with cGMP and ICH Q7 guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.