Description

Dl-Lysine-α-15N Dihydrochloride is a stable isotope-labeled derivative of the essential amino acid lysine, specifically enriched with nitrogen-15 at the alpha position. This compound is a critical reagent for advanced research in metabolic pathway analysis, protein turnover studies, and nutritional science using mass spectrometry and NMR techniques. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialized manufacturers of diagnostic kits and labeled standards.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to quantify intracellular metabolic fluxes in cell culture and microbiological studies.
• Proteomics & Protein Dynamics: Essential for Stable Isotope Labeling by Amino acids in Cell culture (SILAC) experiments to measure protein synthesis and degradation rates.
• Nutritional Research: Employed in clinical and animal studies to investigate lysine metabolism, bioavailability, and requirements.
• Pharmaceutical Development: Serves as an internal standard for the accurate quantification of lysine and related compounds in bioanalytical method development and validation (LC-MS/MS).
• Biochemical Synthesis: Acts as a labeled building block for the synthesis of peptides, proteins, or other complex molecules where isotopic enrichment is required.
• Diagnostic Reagents: Used in the formulation of calibration standards and quality control materials for in-vitro diagnostic testing.

Basic Information

Product Name	Dl-Lysine-α-15N Dihydrochloride
CAS No.	2747-89-9
Molecular Formula	C₆H₁₅¹⁵NCl₂O₂
Molecular Weight	Approx. 221.11 g/mol
Synonyms	Lysine-α-15N dihydrochloride; DL-Lysine-α-15N dihydrochloride; (RS)-2,6-Diaminohexanoic-α-15N acid dihydrochloride; (±)-Lysine-α-15N dihydrochloride; 15N-Labeled DL-lysine dihydrochloride; Lysine (α-15N) hydrochloride; H-Lys-α-15N-OH•2HCl
EINECS	Contact for details

Quality Control

Our Dl-Lysine-α-15N Dihydrochloride is manufactured under strict quality systems to ensure high isotopic and chemical purity, essential for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % 15N), chemical purity (by HPLC), and specific tests for identity and impurities. We adhere to relevant industry standards for research chemicals, ensuring reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 15N)	≥ 98%
Assay (HPLC)	≥ 98.0%
Optical Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.