Description

4-Fluorobenzyl Thiocyanate is a versatile fluorinated organic building block characterized by its reactive benzyl and thiocyanate functional groups. This compound is essential for synthesizing advanced intermediates in pharmaceutical and agrochemical research, where the introduction of fluorine and sulfur-containing moieties is critical for modulating biological activity and physicochemical properties. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the research and production of advanced polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in the design of activity-based probes and bioconjugation reagents for studying enzyme function and protein labeling.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the global life sciences sector.

Basic Information

Product Name	4-Fluorobenzyl Thiocyanate
CAS No.	2740-87-6
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	(4-Fluorophenyl)methyl thiocyanate; p-Fluorobenzyl thiocyanate; 1-(Thiocyanatomethyl)-4-fluorobenzene; 4-Fluorobenzyl isothiocyanate (common misnomer); α-Thiocyanato-4-fluorotoluene; 4-Fluorobenzyl rhodanide; 4-Fluoro-α-thiocyanatotoluene; FBT
EINECS	220-369-6

Quality Control

Every batch of 4-Fluorobenzyl Thiocyanate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, NMR, and IR is supplied with each shipment. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.