Description

3-(Trifluoromethyl)Benzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique combination of the benzylamine functionality and the electron-withdrawing trifluoromethyl group, which imparts enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF₃ group can improve biological activity and environmental persistence profiles.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Polymer & Material Science: Incorporated into monomers for high-performance polymers, resins, and liquid crystals to modify thermal stability and optical properties.
• Fluorinated Dye & Pigment Intermediates: Employed in the synthesis of specialty dyes and pigments where fluorine substitution alters color fastness and solubility.
• Research & Development: A valuable reagent in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-(Trifluoromethyl)Benzylamine
CAS No.	2740-83-2
Molecular Formula	C₈H₈F₃N
Molecular Weight	175.15 g/mol
Synonyms	α-(Trifluoromethyl)-m-toluidine; (3-(Trifluoromethyl)phenyl)methanamine; m-(Trifluoromethyl)benzylamine; 3-(Trifluoromethyl)benzenemethanamine; 3-(Trifluoromethyl)phenylmethylamine; 1-(Aminomethyl)-3-(trifluoromethyl)benzene; Benzenemethanamine, 3-(trifluoromethyl)-
EINECS	220-368-7

Quality Control

Our 3-(Trifluoromethyl)Benzylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Impurity A	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.