Description

3,4-Dichloro-6-Fluoroaniline is a halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a multifunctional aromatic core for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen-substituted patterns into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring a specific halogenated aniline scaffold.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the dichloro-fluoro substitution pattern confers specific biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing complex, high-performance dyes and organic pigments.
• Material Science Research: Employed in the development of novel polymers and liquid crystals that incorporate halogenated aromatic amines for modified material properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create more complex amine derivatives.

Basic Information

Product Name	3,4-Dichloro-6-Fluoroaniline
CAS No.	2729-36-4
Molecular Formula	C6H4Cl2FN
Molecular Weight	180.01 g/mol
Synonyms	2-Fluoro-4,5-dichloroaniline; 4,5-Dichloro-2-fluoroaniline; 6-Fluoro-3,4-dichloroaniline; 3,4-Dichloro-6-fluoro-benzenamine; Benzenamine, 3,4-dichloro-6-fluoro-; 2-Fluoro-4,5-dichlorobenzenamine
EINECS	220-350-4

Quality Control

Our 3,4-Dichloro-6-Fluoroaniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for use in sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.