Description

5-Bromo-2-Fluoroaniline is a halogenated aniline derivative serving as a versatile and high-value organic intermediate. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical building block for introducing specific functionalities into more complex molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and advanced materials.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the bromo and fluoro groups enhance compound stability and efficacy.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport or host materials in OLED devices.
• Dyestuff and Pigment Manufacturing: Employed in the synthesis of specialized, high-performance dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.

Basic Information

Product Name	5-Bromo-2-Fluoroaniline
CAS No.	2724-09-6
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Fluoro-5-bromoaniline; 5-Bromo-2-fluoro-benzenamine; 1-Amino-5-bromo-2-fluorobenzene; Benzenamine, 5-bromo-2-fluoro-; 5-Bromo-2-fluorophenylamine; 2-Fluoro-5-bromophenylamine; 5-Bromo-o-fluoroaniline
EINECS	220-333-8

Quality Control

Our 5-Bromo-2-Fluoroaniline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.