Description

2-Fluoro-4-Iodophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. Its unique structure, featuring both fluorine and iodine substituents, makes it an essential intermediate for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides where the fluorine and iodine groups modulate biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and photoactive materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-Iodophenol
CAS No.	2713-28-2
Molecular Formula	C6H4FIO
Molecular Weight	237.99 g/mol
Synonyms	4-Iodo-2-fluorophenol; 2-Fluoro-4-iodo-1-hydroxybenzene; Phenol, 2-fluoro-4-iodo-; 2-Fluoro-4-iodophenol; 4-Iodo-2-fluorophenol; 1-Hydroxy-2-fluoro-4-iodobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Iodophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles for production, ensuring reliability for critical applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.