Description

Ergocryptine Methanesulfonate is a semi-synthetic ergot alkaloid derivative, specifically the methanesulfonate salt form of ergocryptine. This compound is of significant commercial and research interest due to its potent biological activity as a dopamine receptor agonist. It is primarily utilized in the pharmaceutical and life science sectors for advanced research, process development, and as a critical reference standard. Professionals in pharmaceutical R&D, analytical chemistry, and biochemical manufacturing seek this high-purity compound for its reliable performance and consistent quality.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the quality control and assay validation of pharmaceutical products and raw materials containing ergot alkaloids.
• Biochemical Research: Used as a potent and selective dopamine D2 receptor agonist in neurological and endocrine research to study receptor mechanisms and signal transduction pathways.
• Process Development & Scale-up: Employed as a key intermediate or model compound in the development and optimization of synthetic routes for complex alkaloid-based APIs (Active Pharmaceutical Ingredients).
• Analytical Method Development: Essential for developing and calibrating sensitive analytical methods such as HPLC, LC-MS, and UV spectroscopy for the detection and quantification of ergot derivatives.
• Academic & Institutional Research: Supports fundamental studies in pharmacology, neurochemistry, and medicinal chemistry within university and government research laboratories.

Basic Information

Product Name	Ergocryptine Methanesulfonate
CAS No.	2706-66-3
Molecular Formula	C32H41N5O5 · CH3SO3H
Molecular Weight	671.80 g/mol
Synonyms	Ergocryptine Mesylate; 2-Ergocryptine Methanesulfonate; Dihydroergocryptine Methanesulfonate; (5'α)-Ergoline-8-carboxamide, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, compound with methanesulfonic acid (1:1); 9,10-Didehydro-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione methanesulfonate; UCB 1545; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ergocryptine Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and impurity profiling, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.