Description

D-Sphingosine Hcl CAS NO 2673-72-5 is a high-purity, hydrochloride salt derivative of the fundamental sphingolipid backbone, D-sphingosine. This compound is a critical biochemical building block and signaling molecule, essential for research into cellular processes like apoptosis, proliferation, and differentiation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, metabolic studies, and the synthesis of complex sphingolipids.

Application

• Biochemical Research & Drug Discovery: A key precursor and intermediate in studying sphingolipid metabolism, cell signaling pathways, and as a target for novel therapeutic agents.
• Pharmaceutical Intermediate: Used in the synthesis of more complex sphingolipid analogs and potential active pharmaceutical ingredients (APIs) targeting neurological and oncological diseases.
• Cell Biology Studies: Employed to investigate its role in cellular processes such as programmed cell death (apoptosis), cell cycle regulation, and response to stress.
• Enzyme Substrate & Inhibitor Studies: Serves as a substrate for enzymes like sphingosine kinases and ceramide synthases in kinetic and functional assays.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
• Cosmeceutical Research: Investigated for its potential role in skin barrier function and as an ingredient in advanced dermatological formulations.

Basic Information

Item	Detail
Product Name	D-Sphingosine Hcl
CAS No.	2673-72-5
Molecular Formula	C18H38ClNO2
Molecular Weight	335.96 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxyoctadec-4-ene hydrochloride; D-erythro-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride; (E)-Sphing-4-enine hydrochloride; Sphingosine (D-erythro) hydrochloride; Sphing-4-enine, (2S,3R,4E)-2-amino-1,3-dihydroxy- hydrochloride; Sphingosine HCl; 4E-Sphingosine hydrochloride
EINECS	Contact for details

Quality Control

Our D-Sphingosine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.