Description

Phe-Phe-Phe-Phe Acetate Salt CAS NO 2667-02-9 is a high-purity tetrapeptide derivative, specifically the acetate salt of the L-phenylalanine tetramer. This compound is a critical building block and research tool in advanced biochemical and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, drug discovery, and material science who require precise, high-quality intermediates for their processes.

Application

• Peptide Synthesis Intermediate: Serves as a key protected fragment or a model compound for the solid-phase and solution-phase synthesis of longer, more complex peptide chains.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those involving proteases or peptidases, to investigate cleavage specificity and kinetics.
• Amyloid Research: Acts as a model system for studying β-sheet formation, aggregation, and amyloid fibril formation due to the hydrophobic nature of the phenylalanine residues.
• Pharmaceutical Development: Employed in the discovery and development of novel therapeutic agents, including enzyme inhibitors and candidates for neurodegenerative diseases.
• Material Science: Investigated for the creation of peptide-based nanomaterials and hydrogels, leveraging its self-assembly properties.
• Academic & Industrial R&D: Provides a well-defined, high-purity compound for method development, analytical calibration, and proof-of-concept studies across various scientific disciplines.

Basic Information

Item	Detail
Product Name	Phe-Phe-Phe-Phe Acetate Salt
CAS No.	2667-02-9
Molecular Formula	C48H52N4O6 • xC2H4O2
Molecular Weight	780.97 g/mol (Free base)
Synonyms	L-Phenylalanyl-L-phenylalanyl-L-phenylalanyl-L-phenylalanine acetate salt; FFFF acetate; Tetraphenylalanine acetate; H-Phe-Phe-Phe-Phe-OH • AcOH; (Phe)4 acetate; NSC 334286; Boc-Phe-Phe-Phe-Phe-OMe (related protected form); Poly-phenylalanine peptide fragment
EINECS	Contact for details

Quality Control

Every batch of Phe-Phe-Phe-Phe Acetate Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), residual solvents, acetate content, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of water. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total Peptide Content)
Acetate Content	1.0 - 2.0 eq (by titration)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.