Description

Ethyl n-Benzoyl-L-Argininate Hydrochloride is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and biochemical research. This compound serves as a critical building block, offering a protected arginine side chain that is stable under standard coupling conditions, thereby enabling the efficient production of complex peptides. It is primarily utilized by pharmaceutical R&D teams, peptide manufacturers, and academic laboratories focused on developing therapeutic agents, enzyme inhibitors, and novel bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of L-arginine into peptide chains.
• Pharmaceutical Research: Used in the development of peptide-based drugs targeting cardiovascular, metabolic, and oncological pathways.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides and affinity probes for diagnostic and research applications.
• Enzyme Substrate & Inhibitor Studies: Employed in biochemical assays to study protease activity and design specific inhibitors.
• Custom Peptide Service Providers: A fundamental raw material for CROs and CDMOs offering bespoke peptide production.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Ethyl n-Benzoyl-L-Argininate Hydrochloride
CAS No.	2645-08-1
Molecular Formula	C15H23N5O3 • HCl
Molecular Weight	373.84 g/mol (Free base: 337.38)
Synonyms	Benzoyl-L-arginine ethyl ester hydrochloride; BAEE Hydrochloride; Nα-Benzoyl-L-arginine ethyl ester hydrochloride; L-Arginine, N2-benzoyl-, ethyl ester, hydrochloride; Ethyl N-benzoyl-L-argininate hydrochloride; Bz-Arg-OEt • HCl; N-Benzoyl-L-arginine ethyl ester monohydrochloride; Trypsin substrate BAEE
EINECS	220-161-7

Quality Control

Our Ethyl n-Benzoyl-L-Argininate Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using desiccant packs in a secondary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +18.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0% L-Isomer
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.