Description

H-γ-Glu-4-Abz-Oh is a specialized amino acid derivative, specifically a γ-glutamyl conjugate of 4-aminobenzoic acid. This compound serves as a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, peptide synthesis, and biochemical research sectors for developing novel compounds and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a modified amino acid residue in the solid-phase and solution-phase synthesis of specialized peptides and peptidomimetics.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies, particularly those involving γ-glutamyl transpeptidases or related enzymes.
• Prodrug Development: Investigated for its potential in designing prodrugs to enhance the solubility, stability, or targeted delivery of therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	H-γ-Glu-4-Abz-Oh
CAS No.	2643-70-1
Molecular Formula	C₁₂H₁₄N₂O₅
Molecular Weight	266.25 g/mol
Synonyms	H-γ-Glu-4-Abz-OH; γ-L-Glutamyl-4-aminobenzoic acid; L-γ-Glutamyl-4-aminobenzoate; 4-[(4-Aminobenzoyl)amino]-5-carboxypentanoic acid; (2S)-2-Amino-5-[[(4-aminophenyl)carbonyl]amino]-5-oxopentanoic acid; N-(4-Aminobenzoyl)-L-glutamic acid; H-Glu(4-Abz)-OH
EINECS	Contact for details

Quality Control

Our H-γ-Glu-4-Abz-Oh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.