Description

Benzylpenicilloyl is a key chemical derivative of penicillin, representing the penicilloyl hapten group. This compound is essential for research and development in the field of immunology and allergy diagnostics. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions studying drug hypersensitivity reactions. Its well-defined structure makes it a critical reference standard for investigating penicillin-related allergies.

Application

• Immunological Research: Serves as a critical hapten for studying the mechanism of penicillin allergy and immune response.
• Diagnostic Reagent Development: Used as a reference standard or conjugate in the production of in-vitro diagnostic (IVD) kits for detecting penicillin-specific IgE antibodies.
• Pharmaceutical Impurity Profiling: Employed as a marker or standard in analytical methods to identify and quantify penicillin-derived impurities in drug substances and products.
• Allergen Characterization: Fundamental for mapping antigenic determinants and understanding the cross-reactivity patterns of β-lactam antibiotics.
• Bioconjugation Studies: Acts as a model compound for developing conjugation techniques to proteins like human serum albumin (HSA) for immunological assays.
• Reference Standard: Provides a certified material for quality control and method validation in regulatory and compliance testing within the pharmaceutical industry.

Basic Information

Product Name	Benzylpenicilloyl
CAS No.	2642-55-9
Molecular Formula	C16H20N2O5S
Molecular Weight	352.41 g/mol
Synonyms	BPO; Penicilloyl Group; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Benzylpenicilloyl hapten; Phenylacetylpenicilloyl; Penicilloyl determinant; Major antigenic determinant of penicillin; Penicilloyl poly-L-lysine (PPL) derivative component
EINECS	220-161-7

Quality Control

Our Benzylpenicilloyl is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support compliance with relevant pharmacopeial guidelines for reference standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.