Description

3-Chloro-4-Fluorophenol is a versatile halogenated phenol derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable intermediate for creating compounds with specific electronic and steric properties. This chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the phenol moiety acts as a versatile handle for further functionalization.
• Liquid Crystal & Electronic Materials: Serves as a starting material for synthesizing specialty chemicals used in liquid crystal displays (LCDs) and organic electronic components.
• Polymer Modification: Acts as a monomer or additive to introduce halogenated phenolic groups into polymer chains, altering thermal stability and flame retardancy.
• Dye & Pigment Manufacturing: Intermediate in the production of complex dyes and organic pigments, contributing to color fastness and molecular stability.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	3-Chloro-4-Fluorophenol
CAS No.	2613-23-2
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	4-Fluoro-3-chlorophenol; 3-Chloro-4-fluorophenol; 1-Chloro-2-fluoro-4-hydroxybenzene; Phenol, 3-chloro-4-fluoro-; 3-Cl-4-F-Phenol; 4-Hydroxy-2-fluorochlorobenzene; 2-Fluoro-5-chlorophenol
EINECS	220-045-6

Quality Control

Our 3-Chloro-4-Fluorophenol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.