Description

H-Pro-Gly-Oh CAS NO 2578-57-6 is a high-purity dipeptide derivative, specifically L-Hydroxyprolyl-Glycine, serving as a critical building block in advanced organic synthesis. Its value lies in providing a structurally defined scaffold for the development of novel bioactive compounds and complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Serves as a protected dipeptide unit in solid-phase and solution-phase peptide synthesis for creating custom sequences.
• Cosmetic Peptides: A potential raw material for synthesizing bioactive peptides used in anti-aging and skin-repair cosmetic formulations.
• Chemical Biology Probes: Utilized to construct molecular probes for studying protein-protein interactions and cellular processes.
• Academic & Industrial R&D: A fundamental reagent for medicinal chemistry programs and the development of new therapeutic candidates.

Basic Information

Product Name	H-Pro-Gly-Oh
CAS No.	2578-57-6
Molecular Formula	C7H12N2O4
Molecular Weight	188.18 g/mol
Synonyms	L-Hydroxyprolylglycine; (2S,4R)-4-Hydroxyprolylglycine; Glycine, L-4-hydroxyprolyl-; H-Hyp-Gly-OH; H-L-Hyp-Gly-OH; 4-Hydroxy-L-prolylglycine; 4(R)-Hydroxy-L-prolylglycine; NSC 334855
EINECS	219-937-5

Quality Control

Our H-Pro-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-70° to -80° (c=1 in H2O)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.