Description

H-Gly-Leu-Gly-Oh is a tripeptide composed of glycine and leucine residues, with the CAS registry number 2576-67-2. This compound serves as a crucial building block and intermediate in advanced peptide synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions for developing novel therapeutic agents and studying peptide structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of longer, biologically active peptide chains for drug discovery.
• Biochemical Research: Used as a standard or model compound in enzymatic studies, proteomics research, and investigations into peptide metabolism and stability.
• Cosmetic Peptide Synthesis: Serves as a foundational unit for constructing specialized peptides used in advanced skincare and cosmetic formulations.
• Academic & Laboratory Use: Employed in university and institutional labs for teaching peptide chemistry principles and conducting fundamental research.
• Enzyme Substrate Studies: Acts as a specific substrate for studying the activity and kinetics of proteolytic enzymes like peptidases and proteases.
• Nutraceutical Development: Investigated for potential use in the development of bioactive peptide supplements and functional food ingredients.

Basic Information

Item	Details
Product Name	H-Gly-Leu-Gly-Oh
CAS No.	2576-67-2
Molecular Formula	C11H21N3O4
Molecular Weight	259.30 g/mol
Synonyms	Glycyl-L-leucylglycine; G-L-G-OH; H-Gly-Leu-Gly-OH; Gly-Leu-Gly; L-Leucylglycylglycine; NSC 334358; Glycine, L-leucylglycyl-; Tripeptide Gly-Leu-Gly
EINECS	219-933-8

Quality Control

Our H-Gly-Leu-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-30° to -35° (c=1 in Acetic Acid)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.