Description

2-Fluorothiophenol is a versatile organosulfur building block characterized by the presence of both fluorine and a thiol functional group. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of sulfur-containing heterocycles and fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for metal-complexing ligands in catalysis and material science applications.
• Polymer and Material Science: Employed in the modification of polymers and the creation of specialty monomers to impart specific chemical or physical properties.
• Organic Synthesis Reagent: Acts as a nucleophile or a coupling partner in various cross-coupling reactions and functional group transformations.
• Chemical Research & Development: Essential for exploratory chemistry in academic and industrial R&D labs for developing new synthetic methodologies.

Basic Information

Product Name	2-Fluorothiophenol
CAS No.	2557-78-0
Molecular Formula	C6H5FS
Molecular Weight	128.17 g/mol
Synonyms	2-Fluorobenzenethiol; o-Fluorothiophenol; 2-Fluorophenyl mercaptan; 1-Fluoro-2-mercaptobenzene; Benzenethiol, 2-fluoro-; (2-Fluorophenyl)thiol; 2-Fluoro-thiophenol; o-Fluorobenzenethiol
EINECS	219-875-1

Quality Control

Our 2-Fluorothiophenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity assay and impurity profile via GC/HPLC. A Certificate of Analysis (COA) is supplied with each shipment, detailing specifications and test results. Our quality system supports compliance with cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.