Description

n-Formylglycine is a key organic intermediate and a derivative of the amino acid glycine. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a precursor and a model compound for studying enzyme mechanisms and post-translational modifications. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers. Our supply of n-Formylglycine CAS NO 2491-15-8 ensures high purity and consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and peptide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for sulfatases, where it mimics the formylglycine residue critical for catalytic activity.
• Peptide Chemistry: Acts as a protected glycine derivative in solid-phase and solution-phase peptide synthesis to modify peptide properties.
• Proteomics & Metabolomics: Employed as a standard or reference compound in mass spectrometry and analytical studies for biomarker research.
• Fine Chemical Synthesis: A versatile reagent for constructing heterocyclic compounds and other specialty organic molecules.
• Academic Research: Utilized in university and institutional labs for investigating protein modification pathways and developing new biocatalysts.

Basic Information

Product Name	n-Formylglycine
CAS No.	2491-15-8
Molecular Formula	C3H5NO3
Molecular Weight	103.08 g/mol
Synonyms	Formylglycine; 2-Formamidoacetic Acid; N-Formylglycine; Glycine, N-formyl-; 2-(Formylamino)acetic Acid; Formyl-Gly-OH; FGly; UNII-9K3855P5F6
EINECS	219-667-6

Quality Control

Our n-Formylglycine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.