Description

Gly-Gly-Gly-Gly-Oet is a high-purity, synthetic tetrapeptide derivative, specifically the ethyl ester of tetraglycine. This compound serves as a crucial building block and research intermediate in advanced biochemical synthesis and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis sectors for developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a model substrate in enzymatic studies, particularly for proteases and peptidases, to investigate cleavage specificity and kinetics.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing peptide-based drug candidates and molecular probes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS analyses within QC laboratories.
• Material Science: Potential use in the development of bio-inspired materials and hydrogels due to its peptide backbone.

Basic Information

Item	Details
Product Name	Gly-Gly-Gly-Gly-Oet
CAS No.	2437-59-4
Molecular Formula	C12H21N4O5
Molecular Weight	301.32 g/mol
Synonyms	Glycylglycylglycylglycine ethyl ester; Tetraglycine ethyl ester; Ethyl tetraglycinate; H-Gly-Gly-Gly-Gly-OEt; NSC 334280; L-Glycyl-glycyl-glycyl-glycine ethyl ester; Glycine, N-[N-[N-(2-aminoacetyl)glycyl]glycyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Gly-Gly-Gly-Gly-Oet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.