Description

p-Fluoro-(2-Hydroxyhexafluoroisopropyl)Benzene is a high-value fluorinated aromatic building block characterized by its unique combination of a fluorine substituent and a highly fluorinated alcohol moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate sophisticated fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Building block for creating advanced herbicides and pesticides with improved environmental profile and efficacy.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Serves as a monomer or modifier to introduce fluorine into polymers, enhancing chemical resistance and surface properties.
• Organic Electronics: Intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Complex Ligand Synthesis: Precursor for fluorinated ligands used in catalysis and material science.

Basic Information

Product Name	p-Fluoro-(2-Hydroxyhexafluoroisopropyl)Benzene
CAS No.	2402-74-6
Molecular Formula	C9H5F7O
Molecular Weight	262.12 g/mol
Synonyms	1-Fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzene; 4-Fluoro-α,α-bis(trifluoromethyl)benzyl alcohol; Hexafluoroacetone p-fluorophenylhydrate; 2-(4-Fluorophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol; p-Fluoro-α,α-bis(trifluoromethyl)benzyl alcohol; 4-Fluoro-(2-hydroxyhexafluoroisopropyl)benzene; α,α-Bis(trifluoromethyl)-4-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our p-Fluoro-(2-Hydroxyhexafluoroisopropyl)Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flame. Ensure containers are kept tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.