Description

Nalpha-Acetyl-D-Arginine Dihydrate is a high-purity, protected derivative of the non-essential amino acid D-Arginine. This compound is critical for advanced peptide synthesis and biochemical research, offering enhanced stability and controlled reactivity. It serves as a key chiral building block for pharmaceutical R&D, particularly in the development of peptide-based therapeutics, diagnostic agents, and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of novel peptide drugs and bioactive molecules.
• Biochemical Research: Used in enzymatic studies, substrate specificity assays, and as a standard in analytical chromatography.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS) to prevent side reactions.
• Proteomics & Cell Culture: Employed in media formulation and as a tool compound to study arginine metabolism and nitric oxide pathways.
• Cosmetic Peptides: A potential ingredient in the synthesis of anti-aging and skin-conditioning peptide sequences.

Basic Information

Product Name	Nalpha-Acetyl-D-Arginine Dihydrate
CAS No.	2389-86-8
Molecular Formula	C8H16N4O3 · 2H2O
Molecular Weight	248.25 g/mol (Anhydrous Basis)
Synonyms	N-α-Acetyl-D-arginine dihydrate; Ac-D-Arg-OH · 2H2O; (R)-2-Acetamido-5-guanidinopentanoic acid dihydrate; D-Arg(Ac)-OH dihydrate; N-Acetyl-D-arginine dihydrate; N-Ac-D-Arg-OH dihydrate; Protected D-Arginine; Nalpha-Acetyl-D-arginine
EINECS	Contact for details

Quality Control

Our Nalpha-Acetyl-D-Arginine Dihydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation by IR and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-Isomer)
Water Content (KF)	12.0% - 15.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.