Description

Ac-Trp-Nh2 is a protected tryptophan derivative, specifically N-Acetyl-L-tryptophanamide, widely used as a key building block in peptide synthesis and pharmaceutical research. This compound is valued for its role in introducing the indole side chain of tryptophan into peptide chains while protecting the amine functionality. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutic peptides and biochemical probes. The product is supplied as a high-purity material suitable for demanding synthetic applications.

Application

• Peptide Synthesis: Serves as a crucial protected amino acid building block (Fmoc or Boc chemistry) for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Used in the research and development of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Employed as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries in drug discovery platforms.
• Neuroscience Research: Utilized in studies related to serotonin synthesis and neurotransmitter analogs due to its tryptophan backbone.

Basic Information

Product Name	Ac-Trp-Nh2
CAS No.	2382-79-8
Molecular Formula	C13H15N3O2
Molecular Weight	245.28 g/mol
Synonyms	N-Acetyl-L-tryptophanamide; Acetyl-L-tryptophan amide; N-Acetyltryptophanamide; L-Tryptophan, N-acetyl-, amide; Nα-Acetyl-L-tryptophanamide; Ac-Trp-NH2; Acetyl tryptophan amide; N-Acetyl-L-tryptophan monoamide
EINECS	219-185-9

Quality Control

Our Ac-Trp-Nh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity, optical rotation for chiral integrity, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	+20.0° to +30.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.