Description

Ac-Tyr-Nhnh2 is a specialized protected amino acid derivative, specifically an N-acetyl-L-tyrosine hydrazide, with the CAS registry number 2381-07-9. This compound serves as a crucial key building block in peptide synthesis and pharmaceutical research, offering a protected tyrosine side chain for controlled coupling reactions. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers involved in developing novel therapeutic peptides and biochemical probes.

Application

• Peptide Synthesis Intermediate: As a key protected amino acid derivative for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Research: Used in the development and discovery of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation Chemistry: The hydrazide functional group enables specific conjugation strategies for labeling proteins or creating antibody-drug conjugates (ADCs).
• Biochemical Tool Development: Employed in creating substrates, inhibitors, or affinity ligands for studying enzyme mechanisms and proteomics.
• Academic & Industrial R&D: A fundamental reagent for organic and medicinal chemistry research in university and corporate settings.
• Reference Standard: Serves as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	Ac-Tyr-Nhnh2
CAS No.	2381-07-9
Molecular Formula	C₁₁H₁₅N₃O₃
Molecular Weight	237.26 g/mol
Synonyms	N-Acetyl-L-tyrosine hydrazide; Ac-L-Tyr-NHNH₂; Nα-Acetyl-L-tyrosine hydrazide; (2S)-2-Acetamido-3-(4-hydroxyphenyl)propanehydrazide; Acetyltyrosine hydrazide; L-Tyrosine, N-acetyl-, hydrazide; Ac-Tyr-NHNH2; N-Acetyltyrosine hydrazide
EINECS	Contact for details

Quality Control

Our Ac-Tyr-Nhnh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, IR, MS). We provide Certificates of Analysis (COA) with detailed batch-specific data to ensure compliance with your research or production standards. Specifications can be tailored to meet pharmaceutical intermediate or high-purity research grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided per COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.