Description

3-Fluoro-4-Nitroaniline is a versatile aromatic amine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom on the aniline ring, makes it a valuable precursor for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, contributing to color fastness and specific hue properties.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research and development of electron-transport materials and emissive layers for display technologies.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for liquid crystal displays (LCDs).
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aryl amines.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic pathways and fluorinated compounds.

Basic Information

Product Name	3-Fluoro-4-Nitroaniline
CAS No.	2369-13-3
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	4-Nitro-3-fluoroaniline; 3-Fluoro-4-nitrobenzenamine; 1-Amino-3-fluoro-4-nitrobenzene; 3-Fluoro-4-nitro-phenylamine; Benzenamine, 3-fluoro-4-nitro-; 3-Fluoro-4-nitro aniline; 3-Fluoro-p-nitroaniline
EINECS	219-143-8

Quality Control

Our 3-Fluoro-4-Nitroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, GC for residual solvents, and IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.