Description

3-Fluoro-5-Nitrophenol is a versatile fluorinated aromatic building block characterized by its phenol and nitro functional groups. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and manufacturers in the life sciences, specialty chemicals, and material science sectors who require high-purity intermediates for coupling reactions and derivatization.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and pigments that benefit from the nitro and phenolic groups.
• Polymer Chemistry: Employed in the creation of specialty polymers and resins, where it can be incorporated to modify thermal or chemical resistance.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.

Basic Information

Product Name	3-Fluoro-5-Nitrophenol
CAS No.	2369-10-0
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	5-Nitro-3-fluorophenol; 3-Fluoro-5-nitro-1-hydroxybenzene; 1-Hydroxy-3-fluoro-5-nitrobenzene; Phenol, 3-fluoro-5-nitro-; 3-F-5-NP; FNP
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.