Description

Z-Lys(Tos)-Oh is a protected amino acid derivative, specifically the Nα-benzyloxycarbonyl (Z) and Nε-tosyl (Tos) protected form of L-lysine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the development of peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled incorporation of lysine residues into peptide chains.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation and Labeling: The reactive amine groups, when selectively deprotected, serve as sites for attaching fluorescent dyes, biotin, or other functional molecules.
• Biochemical Research: Employed in studying protein-protein interactions, enzyme mechanisms, and structure-activity relationships (SAR) of peptides.
• Antigen Synthesis: Key material for synthesizing peptide antigens used in vaccine development and immunological assays.
• Custom Peptide Services: A staple reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide synthesis.

Basic Information

Product Name	Z-Lys(Tos)-Oh
CAS No.	2362-45-0
Molecular Formula	C21H26N2O6S
Molecular Weight	434.51 g/mol
Synonyms	Nα-Carbobenzoxy-Nε-tosyl-L-lysine; Nα-Z-Nε-Tos-L-lysine; Z-Lys(Tos)-OH; (2S)-6-[[(4-Methylphenyl)sulfonyl]amino]-2-[(phenylmethoxy)carbonylamino]hexanoic acid; N2-[(Benzyloxy)carbonyl]-N6-(4-methylbenzenesulfonyl)-L-lysine; Nα-Cbz-Nε-Tos-L-lysine; CBZ-Lys(TOS)-OH; Z-L-Lys(Tos)-OH
EINECS	Contact for details

Quality Control

Our Z-Lys(Tos)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) with detailed specifications are provided to ensure compliance with your research and cGMP-grade manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.