Description

2-Amino-4-[(trifluoromethyl)sulfonyl]phenylamine is a specialized aromatic amine derivative featuring both amino and trifluoromethanesulfonyl (triflyl) functional groups. This unique bifunctional structure makes it a valuable high-purity intermediate for advanced synthesis in demanding chemical sectors. It is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries. The compound's reactivity profile enables its use in constructing complex molecules where the introduction of both an amine handle and an electron-withdrawing sulfone group is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethylsulfonyl moiety can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, dyes, and advanced organic electronic materials.
• Ligand and Catalyst Development: Utilized in organic and organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing properties of the sulfone group.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences and specialty chemical markets.

Basic Information

Product Name	2-Amino-4-[(trifluoromethyl)sulfonyl]phenylamine
CAS No.	2355-16-0
Molecular Formula	C7H7F3N2O2S
Molecular Weight	240.21 g/mol
Synonyms	2-Amino-4-[(trifluoromethyl)sulfonyl]aniline; 4-Amino-2-[(trifluoromethyl)sulfonyl]aniline; 2,4-Diaminophenyl trifluoromethyl sulfone; 1,3-Benzenediamine, 4-[(trifluoromethyl)sulfonyl]-; 4-(Trifluoromethylsulfonyl)-1,3-phenylenediamine; Benzenamine, 2-amino-4-[(trifluoromethyl)sulfonyl]-; 2355-16-0; 4-Trifluoromethanesulfonyl-m-phenylenediamine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-[(trifluoromethyl)sulfonyl]phenylamine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, GC, and NMR is supplied with each shipment. Our quality commitment ensures consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.