Description

5-Chlorocytosine is a halogenated pyrimidine derivative, a key building block in organic synthesis and pharmaceutical research. This compound is valued for its role as a versatile intermediate in the development of nucleoside analogs and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Used in the development of novel pesticides and herbicides based on modified nucleobases.
• Biochemical Research: Serves as a modified cytosine base for studying DNA/RNA interactions, mutagenesis, and enzyme mechanisms.
• Fine Chemical Synthesis: Acts as a building block for creating complex heterocyclic compounds and specialty chemicals.
• Proteomics & Diagnostics: Potential use in the development of probes, labels, and diagnostic assay components.

Basic Information

Product Name	5-Chlorocytosine
CAS No.	2347-43-5
Molecular Formula	C4H4ClN3O
Molecular Weight	145.55 g/mol
Synonyms	5-Chloro-4-aminopyrimidin-2(1H)-one; 5-Chloro-2-hydroxypyrimidin-4-amine; 4-Amino-5-chloro-2(1H)-pyrimidinone; 5-Chloro-4-aminouracil; 5-Chlorocytosin; Cytosine, 5-chloro-; 2(1H)-Pyrimidinone, 5-chloro-4-amino-
EINECS	219-063-5

Quality Control

Our 5-Chlorocytosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.