Description

6-Fluoroindoline is a versatile fluorinated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in the strategic incorporation of a fluorine atom into the indoline scaffold, which is crucial for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the fluorine atom enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated organic electronic materials and functional dyes.
• Chemical Biology Probes: Employed in the design of fluorinated molecular probes and tags for studying biological systems.
• Catalyst & Ligand Development: Acts as a backbone for constructing novel fluorinated ligands in asymmetric catalysis.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Fluoroindoline
CAS No.	2343-23-9
Molecular Formula	C8H8FN
Molecular Weight	137.15 g/mol
Synonyms	6-Fluoro-2,3-dihydro-1H-indole; 1H-Indole, 6-fluoro-2,3-dihydro-; 6-Fluoroindoline; 2,3-Dihydro-6-fluoro-1H-indole; 6-Fluoro-2,3-dihydroindole; 2343-23-9; 6-Fluoroindoline (base)
EINECS	Contact for details

Quality Control

Our 6-Fluoroindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.