Description

5-Fluoroindoline is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a functionalized indoline scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine atoms for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the fluorine moiety enhances bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on heterocyclic systems.
• Ligand and Catalyst Development: Utilized in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent tags or molecular probes for biological imaging and assay development.

Basic Information

Item	Details
Product Name	5-Fluoroindoline
CAS No.	2343-22-8
Molecular Formula	C8H8FN
Molecular Weight	137.15 g/mol
Synonyms	5-Fluoro-2,3-dihydro-1H-indole; 5-Fluoroindoline; 1H-Indole, 5-fluoro-2,3-dihydro-; 2,3-Dihydro-5-fluoro-1H-indole; 5-Fluoro-2,3-dihydroindole; 2343-22-8; 5-Fluoroindolin; 5-Fluorindolin
EINECS	Contact for details

Quality Control

Our 5-Fluoroindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and highly volatile, it is recommended to handle under an inert atmosphere and keep containers tightly sealed when not in use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.