Description

Dl-Threo-Dihydrosphingosine is a synthetic, racemic diastereomer of the essential sphingolipid backbone, dihydrosphingosine. This compound serves as a critical building block and biochemical tool for research into sphingolipid metabolism, cell signaling, and membrane biology. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and cosmetic science industries for synthesizing complex lipids and studying cellular processes.

Application

• Biochemical Research: A key intermediate and standard for studying sphingolipid biosynthesis, metabolism, and the roles of ceramides in cellular signaling pathways.
• Pharmaceutical Development: Used as a precursor in the synthesis of novel therapeutic agents targeting sphingolipid-related diseases, such as cancer, inflammation, and metabolic disorders.
• Cosmetic Science: Employed in R&D for developing advanced skincare formulations that aim to support skin barrier function and cellular health.
• Enzyme Inhibition Studies: Acts as a substrate or inhibitor in assays for enzymes like serine palmitoyltransferase (SPT), crucial for understanding related disorders.
• Lipidomics & Analytical Standards: Serves as a high-purity reference standard for mass spectrometry and chromatography in lipid profiling and quantification.
• Cell Culture & Biology: Used to modulate sphingolipid levels in cell culture models to investigate apoptosis, proliferation, and stress responses.

Basic Information

Product Name	Dl-Threo-Dihydrosphingosine
CAS No.	2304-75-8
Molecular Formula	C18H39NO2
Molecular Weight	301.51 g/mol
Synonyms	(2S,3R)-2-Amino-1,3-octadecanediol (Threo isomer); D-erythro-Dihydrosphingosine (racemic); (±)-threo-Dihydrosphingosine; Dihydro-D-sphingosine; D-erythro-Sphinganine; (2S,3R)-2-Aminooctadecane-1,3-diol; Sphinganine; 2-Amino-1,3-octadecanediol
EINECS	Contact for details

Quality Control

Our Dl-Threo-Dihydrosphingosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.