Description

Cbz-L-Trp-L-Met-L-Asp-L-Phe-Nh2 is a synthetic tetrapeptide derivative featuring a Cbz (carboxybenzyl) protecting group. This compound is a crucial intermediate in peptide synthesis and pharmaceutical research, offering a protected sequence for the controlled construction of larger, biologically active peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes. Its defined structure ensures reproducibility and purity for advanced scientific applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase or solution-phase synthesis of complex peptide-based drugs and candidates.
• Biochemical Research: Used in studies investigating enzyme-substrate interactions, receptor binding assays, and signal transduction pathways.
• Proteomics & Peptide Library Construction: Acts as a defined component for creating specialized peptide libraries used in high-throughput screening for drug discovery.
• Reference Standard: Employed as a chromatographic or spectroscopic standard for quality control and method validation in analytical laboratories.
• Academic Research: Utilized in university and institutional labs for teaching advanced peptide chemistry and exploring new synthetic methodologies.

Basic Information

Product Name	Cbz-L-Trp-L-Met-L-Asp-L-Phe-Nh2
CAS No.	2283-80-9
Molecular Formula	C41H47N7O8S
Molecular Weight	797.92 g/mol
Synonyms	N-Carbobenzoxy-L-tryptophyl-L-methionyl-L-aspartyl-L-phenylalaninamide; Z-Trp-Met-Asp-Phe-NH2; CBZ-Tryptophan-Methionine-Aspartic Acid-Phenylalanine Amide; Z-W-M-D-F-NH2; Benzyloxycarbonyl-Tryptophan-Methionine-Aspartic Acid-Phenylalanine Amide; Nα-Cbz-L-Tryptophyl-L-Methionyl-L-α-Aspartyl-L-Phenylalaninamide; (S)-2-(((S)-1-(((S)-1-(((S)-4-Amino-1-(((benzyloxy)carbonyl)amino)-1,4-dioxobutan-2-yl)amino)-4-(methylthio)-1-oxobutan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-3-phenylpropyl carbamate
EINECS	Contact for details

Quality Control

Our Cbz-L-Trp-L-Met-L-Asp-L-Phe-Nh2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. Our quality system is designed to support cGMP and GLP compliance for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.