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Dl-3-Hydroxynorvaline CAS NO 2280-42-4


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CAS No.:2280-42-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dl-3-Hydroxynorvaline is a non-proteinogenic amino acid derivative of significant interest in synthetic organic chemistry and pharmaceutical research. This compound serves as a versatile chiral building block and intermediate for the synthesis of more complex molecules, including potential active pharmaceutical ingredients (APIs) and peptidomimetics. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates to develop novel therapeutics and study biochemical pathways.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for metabolic and neurological disorders.
  • Peptide Synthesis: Used as a modified amino acid residue in the synthesis of peptidomimetics and constrained peptides to alter biological activity and stability.
  • Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate amino acid metabolism and related pathways.
  • Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in asymmetric catalytic reactions to construct stereogenic centers.
  • Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name Dl-3-Hydroxynorvaline
CAS No. 2280-42-4
Molecular Formula C5H11NO3
Molecular Weight 133.15 g/mol
Synonyms DL-3-Hydroxynorvaline; (±)-3-Hydroxynorvaline; 3-Hydroxy-2-aminopentanoic acid; 2-Amino-3-hydroxypentanoic acid; DL-3-Hydroxy-2-aminovaleric acid; Norvaline, 3-hydroxy-; HNV
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Quality Control

Our Dl-3-Hydroxynorvaline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) DL-mixture (approx. 1:1 ratio)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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