Description

(R)-2-Amino-3-Hydroxy-3-Methylbutanoic Acid is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its unique stereochemistry and functional groups make it a valuable chiral building block for constructing complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutics and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Peptide Synthesis: Used to incorporate specific stereocenters and hydroxy-functionalized side chains into custom peptides for drug discovery and biochemical research.
• Biocatalyst & Enzyme Substrate: Serves as a substrate or inhibitor in enzymatic studies and as a precursor for developing chiral catalysts in asymmetric synthesis.
• Nutritional & Biochemical Research: Investigated for its role in metabolic studies and as a component in specialized cell culture media or diagnostic reagents.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and other high-value specialty chemicals requiring precise stereocontrol.

Basic Information

Product Name	(R)-2-Amino-3-Hydroxy-3-Methylbutanoic Acid
CAS No.	2280-28-6
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(R)-2-Amino-3-hydroxy-3-methylbutyric acid; (R)-3-Hydroxyvaline; D-3-Hydroxyvaline; (R)-3-Hydroxy-3-methylbutanoic acid, 2-amino-; (2R)-2-Amino-3-hydroxy-3-methylbutanoic acid; (R)-3-Methyl-3-hydroxy-2-aminobutyric acid; H-Val(3-OH)-OH; (R)-β-Hydroxyvaline
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-3-Hydroxy-3-Methylbutanoic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.