Description

2,4,6-Trifluorophenol CAS NO 2268-17-9 is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This high-purity chemical is essential for research and production in the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required to modulate biological activity, stability, and material characteristics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing fluorinated aromatic systems to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing modern herbicides, fungicides, and insecticides, where the trifluoromethylphenol moiety contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Acts as a monomer or modifier in the creation of high-performance polymers, resins, and coatings with improved chemical and thermal resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and as a protecting group or directing agent in complex multi-step syntheses.
• Dye & Pigment Manufacturing: Intermediate for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2,4,6-Trifluorophenol
CAS No.	2268-17-9
Molecular Formula	C6H3F3O
Molecular Weight	148.08 g/mol
Synonyms	2,4,6-Trifluorophenol; Phenol, 2,4,6-trifluoro-; 1-Hydroxy-2,4,6-trifluorobenzene; 2,4,6-Trifluoro-1-hydroxybenzene; TFP; 2,4,6-F3C6H2OH
EINECS	218-880-5

Quality Control

Our 2,4,6-Trifluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the demanding requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	38°C - 42°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.