Description

2,4,5-Trifluorophenol is a fluorinated phenolic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for research and production chemists developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors and antibacterial agents.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and pesticides where fluorine atoms enhance biological activity and stability.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Electronics: Intermediate in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Functional Polymer Monomer: Incorporates fluorine and phenolic functionality into specialty polymers for enhanced performance.
• Chemical Research & Development: Serves as a standard reagent and starting material in academic and industrial R&D for novel fluoroorganic chemistry.

Basic Information

Product Name	2,4,5-Trifluorophenol
CAS No.	2268-16-8
Molecular Formula	C6H3F3O
Molecular Weight	148.08 g/mol
Synonyms	2,4,5-Trifluorophenol; 2,4,5-Trifluoro-1-hydroxybenzene; 1-Hydroxy-2,4,5-trifluorobenzene; Phenol, 2,4,5-trifluoro-; 2268-16-8; NSC 406117; 2,4,5-Trifluorobenzenol
EINECS	218-876-7

Quality Control

Our 2,4,5-Trifluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	40-44 °C
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.