Description

2,3,5-Trifluorophenol CAS NO 2268-15-7 is a high-purity fluorinated phenol derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted aromatic structure provides enhanced lipophilicity and metabolic stability, making it invaluable for creating sophisticated molecules. This compound is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for research, development, and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer & Material Science: Acts as a monomer or modifier in the production of specialty polymers, resins, and coatings to impart chemical resistance and thermal stability.
• Organic Electronics: Utilized in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: Employed as a versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	2,3,5-Trifluorophenol
CAS No.	2268-15-7
Molecular Formula	C6H3F3O
Molecular Weight	148.08 g/mol
Synonyms	2,3,5-Trifluorophenol; 1-Hydroxy-2,3,5-trifluorobenzene; Phenol, 2,3,5-trifluoro-; 2,3,5-Trifluoro-1-hydroxybenzene; 2,3,5-Trifluorophenol (stabilized with HQ); 2,3,5-Trifluorophenyl alcohol; HQ stabilized 2,3,5-Trifluorophenol
EINECS	218-880-4

Quality Control

Our 2,3,5-Trifluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest standards of purity and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.