Description

8-(Trifluoromethyl)-7H-Purine is a high-value, fluorinated purine derivative, a key heterocyclic building block in advanced organic synthesis. Its core value lies in the unique properties imparted by the trifluoromethyl group, which is critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel nucleoside analogs, kinase inhibitors, and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold for the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the CF3 group enhances biological efficacy.
• Nucleoside Analog Synthesis: A key precursor for creating modified purine nucleosides with potential therapeutic applications.
• Chemical Biology Probes: Employed in the design of tool compounds and probes to study enzyme mechanisms and cellular pathways.
• Material Science: Investigated as a building block for specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in academic and CRO settings.

Basic Information

Product Name	8-(Trifluoromethyl)-7H-Purine
CAS No.	2268-12-4
Molecular Formula	C6H3F3N4
Molecular Weight	188.11 g/mol
Synonyms	8-(Trifluoromethyl)purine; 7H-Purine, 8-(trifluoromethyl)-; 8-Trifluoromethylpurine; 8-CF3-Purine; 8-Trifluoromethyl-7H-purine; 8-(Trifluoromethyl)-9H-purine (tautomer); Purine, 8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-7H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC / NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.